8-Hydroxydihydrochelerythrine and 8-Hydroxydihydrosanguinarine with a Potent Acetylcholinesterase Inhibitory Activity from Chelidonium majus L.
نویسندگان
چکیده
منابع مشابه
In vitro activity of plant extracts and alkaloids against clinical isolates of extended-spectrum β-lactamase (ESBL)-producing strains.
The antibacterial activity of 80% ethanol extracts of 10 medicinal plants collected in Yunnan (Southwest China), was tested against clinical isolates of extended-spectrum β-lactamase (ESBL)-producing strains. Their MIC values ranged between 1.56-12.50 mg/mL. The most active plant extract was Chelidonium majus L. (MIC = 1.56 mg/mL). Two potent isoquinoline alkaloids, 8-hydroxydihydrosanguinarine...
متن کاملAntibacterial alkaloids from chelidonium majus linn (papaveraceae) against clinical isolates of methicillin-resistant Staphylococcus aureus.
PURPOSE This study describes the antibacterial effect of extracts and compounds isolated from the aerial part of Chelidonium majus Linn. (Papaveraceae) acting against clinical strains of methicillin-resistant Staphylococcus aureus (MRSA). METHODS The activities were evaluated by using the macrobroth dilution method and reported as the MICs/MBCs. RESULTS Bioassay-guided fractionation of the ...
متن کاملChelidonium majus-Induced Acute Hepatitis
Medicinal herbs, defined as preparations concocted by an unauthorized layperson [1], are used widely in Asian countries because they are easily available and are believed to be harmless. Despite this belief, hepatitis, and even fulminant hepatitis, associated with medicinal herbs has been reported. According to previous reports, drug-induced liver injury accounts for 2~40% of all liver injury [...
متن کاملSeasonal variability of Chelidonium majus L. secondary metabolites content and antioxidant activity.
The aim of this study is to investigate the total phenolic content, concentration of flavonoids and antioxidant activity in extracts of the plant Chelidonium majus L. during different phenological stages (stage of rosette, the initial flowering stage, the stage of fully formed flowers and stage of fruits formation). Five different extracts of the whole plant, for each phase, were obtained by ex...
متن کاملEvaluation of anti-inflammatory and analgesic activities of extracts from herb of Chelidonium majus L.
The aim of the study was to evaluate analgesic activity ("hot plate" test), anti-inflammatory activity (carrageenan-induced paw edema) and locomotor activity in rats under the influence of three fractions of Chelidonium majus herb extract: full water extract (FWE), protein enriched fraction (PEF), and non-protein fraction (NPF). Effects of the fractions on the level of chosen cytokines and thei...
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ژورنال
عنوان ژورنال: Biological and Pharmaceutical Bulletin
سال: 2006
ISSN: 0918-6158,1347-5215
DOI: 10.1248/bpb.29.2317